Volume 8, Issue 5, September 2020, Page: 66-71
Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo
Vangu Vangu Roland, Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo; Department of Internal Medecine, University of Président Joseph KASA-VUBU, Boma, Democratic Republic of Congo
Rahma Rashid Tozin, Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Mbuyi Muamba Jean Marie, Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo
Mokondjimobe Etienne, Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo; Department of Sciences, Universityof Marien Ngouabi, Brazzaville, Republic of Congo
Mambueni Thamba Christophe, Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Vangu Ngoma Dieudonné, Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Tsimba Vangu Andrien, Department of Internal Medecine, University of Président Joseph KASA-VUBU, Boma, Democratic Republic of Congo
Makoso Nimi Blaise, Department of Internal Medecine, University of Président Joseph KASA-VUBU, Boma, Democratic Republic of Congo
Mbungu Fuele Simon, Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Nkodila Natuhoyila Aliocha, Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Longo-Mbenza Benjamin, Départment of Gynécology and Obstétric, University of Kinshasa, Kinshasa, Democratic Republic of Congo; Department of Internal Medicine, Walter Sisulu University, Mthatha, South Africa; Department of Public Health, Lomo-University Reseach, Kinshasa, Democratic Republic of Congo
Received: Aug. 6, 2020;       Accepted: Aug. 24, 2020;       Published: Sep. 25, 2020
DOI: 10.11648/j.ejpm.20200805.12      View  56      Downloads  42
Abstract
Background and aims: the progression of preeclampsia continues to increase in sub-Saharan Africa where care is inadequate. The objective of this study is to identify factors associated with the progression of preeclampsia at University Clinics of Kinshasa. Methods: This is a prospective and analytical study of 265 patients hospitalized at the Gynecology Service of the University Clinics of Kinshasa between January 1, 2006 and December 31, 2015. The clinical, biological, therapeutic and evolutionary characteristics were the parameters of 'interest. Cox regression in multivariate analyzes was generated to identify risk factors for progression to the p <0.05 threshold. Results: The cumulative frequency of preeclapse decreased from 6.0% in the first year to 64.2% at the end of the study with periods of stagnation in the rate. Predictors of the progression of preeclampsia in the study population for F values equal to 2.86, 2.10, 3.57, 3.23, 2.81 and 0.005 and an α risk equal at 0.009; 0.014; 0.006; 0.007; 0.005 and 0.006 0.0005, respectively, for age, level of education, occupation, SAP, DBP and figure 3, led us to reject the null hypothesis of equality of means between progression and the lack of progression. In multiple cox regression, the risk of progression of preeclampsia was 3 times respectively in parturients aged > 35 years (aRR: 2.57 95% CI: 1.89-4.75), in female employees (aRR: 2.83 95% CI: 1.97-4.46); this risk was 2 times respectively among academics, PAS and PAD elevated. Treatment under scheme 3, on the other hand, reduced the risk of progression 2 (aRR: 0.43 95% CI: 0.28-0.63). Conclusion: the progression of pre-eclampsia could be linked to certain socio-demographic and clinical factors. The role played by the treatment regimen of αmethyl Dopa + Nifedipine + Diazepam remains to be defined in this subgroup.
Keywords
Progression, Preeclampsia, Risk Factors, CUK
To cite this article
Vangu Vangu Roland, Rahma Rashid Tozin, Mbuyi Muamba Jean Marie, Mokondjimobe Etienne, Mambueni Thamba Christophe, Vangu Ngoma Dieudonné, Tsimba Vangu Andrien, Makoso Nimi Blaise, Mbungu Fuele Simon, Nkodila Natuhoyila Aliocha, Longo-Mbenza Benjamin, Factors Associated with the Progression of Preeclampsia at Kinshasa University Clinics in Democratic Republic of Congo, European Journal of Preventive Medicine. Vol. 8, No. 5, 2020, pp. 66-71. doi: 10.11648/j.ejpm.20200805.12
Copyright
Copyright © 2020 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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