Volume 7, Issue 6, December 2019, Page: 117-122
Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People
Nowshin Monir, Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh
Zebunnesa Zeba, Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh
Sharmin Sultana, Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh
Ijajul Islam, Department of Public Health and Informatics, Jahangirnagar University, Dhaka, Bangladesh
Received: Oct. 23, 2019;       Accepted: Nov. 12, 2019;       Published: Nov. 26, 2019
DOI: 10.11648/j.ejpm.20190706.15      View  28      Downloads  13
Abstract
Background: Microalbuminuria is a clinical marker of glomerular injury and identified as a risk of progressive renal damage, cardiovascular disease and morbidity. Hypertension (HTN) is a worldwide public health problem andcommonly coexists with Diabetes Mellitus (DM). Objective: The aim of the study was todetermine the prevalence of microalbuminuriain type 2diabetic patients and general people and the relationship between microalbuminuria withHTN and other clinical parametersin these twogroups of people. Methodology: A cross-sectional study was carried out using a pretested structured questionnaire amongrandomly selected107 participants aged from 35-70 years. Out of 107 participants 64 persons were type 2 diabetic patients and 43 were healthy individuals. Biochemical analysis of blood and urine samples was performed. Result: The prevalence of microalbuminuria was 17.2% in diabetic patients and 25.6% ingeneral people whereas the prevalence of HTN was 48.4% among diabetic patients and 51.6% in normal healthy persons. Regardless of the group considered, when microalbuminuria was analyzed according to the different clinical parameters, microalbuminuricpatients had significantly highersystolic (p=0.03) diastolic (p=0.02) blood pressure, urine creatinine (p=0.000), serum creatinine (p=0.012), urine albumin (p=0.019) and GFR (p=0.000). Microalbuminuria was found to be associated with HTN (odds ratio [OR] 3.5, 95% confidence interval [CI] 1.2-9.7). Conclusion: The study concluded thatmicroalbuminuria prevalence is high among general people and HTN has a significant relationship with microalbuminuria. These findings suggest early screening of microalbuminuria and the proper management of other clinical parameters to halt and prevent end stage renal disease and cardiovascular risk in future.
Keywords
Microalbuminuria, Hypertension, Type 2 Diabetes Mellitus, General People
To cite this article
Nowshin Monir, Zebunnesa Zeba, Sharmin Sultana, Ijajul Islam, Determination of Microalbuminuraia and Its Relation to HTN in Type 2 Diabetic Patients and General People, European Journal of Preventive Medicine. Vol. 7, No. 6, 2019, pp. 117-122. doi: 10.11648/j.ejpm.20190706.15
Copyright
Copyright © 2019 Authors retain the copyright of this article.
This article is an open access article distributed under the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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