Volume 1, Issue 3, November 2013, Page: 58-62
Seroepidemiology of Rubella IgG among Unvaccinated Pregnant Women Attending Antenatal Clinics from Two Rural Communities in Plateau State, Nigeria
Bigwan Emmanuel Isa, Department of Medical Laboratory Science, University of Jos, P.M.B.2084, Nigeria
Egah Daniel Zanyu, Department of Medical Microbiology, Jos University Teaching Hospital Jos, Nigeria
Badung Bitrus Pam, Department of Medical Microbiology, Jos University Teaching Hospital Jos, Nigeria; APIN/PEPFAR Centre, Jos University Teaching Hospital, Jos, Nigeria
Danung Monday, Department of Medical Microbiology, Jos University Teaching Hospital Jos, Nigeria; APIN/PEPFAR Centre, Jos University Teaching Hospital, Jos, Nigeria
Received: Dec. 11, 2013;       Published: Dec. 30, 2013
DOI: 10.11648/j.ejpm.20130103.12      View  2414      Downloads  93
Abstract
Background: Rubella is a mild illness with most cases goes undiagnosed because of its sub clinical nature. However, the disease poses serious threat such as congenital rubella defects, abortions, and still birth if a pregnant woman contracted the infection during her first trimester. Unfortunately lack of sufficient data on its prevalence and incidence with unavailability of rubella vaccines in our antenatal clinics is of great dangers to our sero-negative women with their unborn babies. Objective: To determine the sero-prevalence of rubella IgG within the two Nigerian communities. Methods: Two hundred and sixty seven (267) pregnant women attending antenatal clinics in Mangu and Pankshin General Hospital and Primary Health Care (PHC) Clinics were screened for Rubella IgG using ELISA Test kit (Globalemed, Alexandria VA USA) based on the manufacturer’s instructions. Questionnaires were also used to obtain other vital bio-data of patients and results analyzed using SPSS version, 13.0 statistical software package. Results: Out of all the samples screened, 247(92.51%) were seropositive for rubella IgG. Rubella IgG was detected in all age groups and occupational status considered and the results indicated a significant relation with the presence of the antibody (P<0.05). So also, Rubella IgG was also detected from all the different parity groups, some socio-cultural variables, probable clinical manifestations and location. However, the results indicated that there were no significant relationships between the presence of the antibody with these variables (P>0.05).Conclusion: This work indicates that most of the women screened (92.51%) were already immune due to natural exposure to the virus. The remaining 7.49% needs to be protected from being infected with the virus especially during the first trimester of pregnancy which can result to congenital defects with fatal consequences. As such, there is need for more sero-surveys on rubella in the country to support the advocacy for the inclusion of rubella vaccination in the National Programme on Immunization (NPI).
Keywords
Rubella, Pregnant Women, Two Nigerian Communities
To cite this article
Bigwan Emmanuel Isa, Egah Daniel Zanyu, Badung Bitrus Pam, Danung Monday, Seroepidemiology of Rubella IgG among Unvaccinated Pregnant Women Attending Antenatal Clinics from Two Rural Communities in Plateau State, Nigeria, European Journal of Preventive Medicine. Vol. 1, No. 3, 2013, pp. 58-62. doi: 10.11648/j.ejpm.20130103.12
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